Biophysical characterization across research areas
Every field has its own unique binding questions. The inQuiQ provides label-free biophysical characterization for studying biomolecular interactions, binding affinity, and kinetics.
One label-free biosensor for all your binding questions
Engineered Antibodies
Characterize affinity and kinetics across monoclonals, bispecifics, nanobodies, and fragments. Rank clones by off-rate, run epitope binning, and confirm binding.
Epitope binning
Off-rate ranking
Small molecules & Peptides
Measure label-free binding for fragments, inhibitors, allosteric modulators, and peptides. Resolve weak binders and confirm binding site and mechanism.
Single-cycle kinetics
IC50 and EC50
Molecular Glues & PROTACs
Analyze binding for molecular glues, PROTACs, and PPI modulators. Follow ternary complex formation and stability, separating binary from ternary binding.
Ternary complex
Cooperativity
Structural Biology
Add solution-phase protein interaction screening to cryo-EM, X-ray, and NMR. Localize interactions to domains and test predicted interfaces.
Competitive assay
protein interaction analysis
Complex Biological Matrices
Analyze binding in serum, plasma, CSF, urine, and cell culture supernatant. Follow biomarkers, drug concentrations, cytokines, and ADAs in real time.
Matrix effect
ADA and PK kinetics
Bioprocessing
Track active concentration and binding across clone selection, purification, and formulation. Compare batches and confirm quality.
Batch comparability
In-process testing
Nucleic Acids
Measure label-free binding for aptamers, ASOs, siRNA, and mRNA. Follow hybridization and DNA protein interactions.
Hybridization kinetics
Aptamer screening
Membrane Proteins
Measure binding to GPCRs, ion channels, and transporters in detergent, nanodisc, or vesicle format. Study targets in a lipid bilayer.
Nanodisc and vesicle
Detergent stabilized
EVs & LNPs
Measure surface markers, targeting ligands, and receptor binding on EVs and lipid nanoparticles. Particles stay intact in solution.
Surface markers
Intact particle binding
Aggregated Proteins
Characterize protein aggregation, self-association, and binding behaviour. Compare interactions across monomeric, oligomeric, and aggregated samples.
Self-association
Aggregation effects
Questions about your application?
Tell us what you're measuring and we'll tell you whether the inQuiQ fits.
Talk to a specialist
Talk to a specialist
Application notes, publications, and data
From small molecule kinetics to antibody affinity, explore real binding data generated on the inQuiQ. Each application note pairs a sensorgram with the affinity and kinetic values behind it.
